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  • 1.  Intravenous thrombolysis for CRAO

    Posted 20 days ago

    Hello group:

    A few studies have been published recently questioning the value of intravenous thrombolysis for treatment of CRAO:

    Preterre C, et al. Intravenous alteplase versus oral aspirin for acute central retinal artery occlusion within 4.5 h of severe vision loss (THEIA): a multicentre, double-dummy, patient-blinded and assessor-blinded, randomised, controlled, phase 3 trial. Lancet Neurol 2025:24:909-919.

    Ryan SJ, et al. A randomized trial of tenecteplase in acute central retinal artery occlusion. N Engl J Med 2026:394:442-450.

    Have you or your institutions used this information to curtail IV thrombolysis for CRAO, or are you still treating and waiting for more data?

    Thanks for your input.

    Eugene May

    University of Washington



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  • 2.  RE: Intravenous thrombolysis for CRAO

    Posted 20 days ago
    Will discuss at the upcoming NANOS meeting! I suggest that you read the two editorials that were published with each of the two articles in The Lancet and the NEJM.
    Valerie

    Sent from my iPhone
    Valerie Biousse, MD
    Emory University
    Atlanta, GA


    Original Message


  • 3.  RE: Intravenous thrombolysis for CRAO

    Posted 20 days ago

    Thank you! The editorials definitely help put things in perspective.

     

    A discussion at NANOS in person will be a great way to help sort issues out.

     

    In the meantime, if the data has affected anyone's institution's practice, I am interested in hearing, as our stroke neurologists are concerned.

    See you next month.


    Eugene

     

    Eugene May, MD | Neuro-ophthalmology

    Professor of Clinical Practice, Department of Ophthalmology

    Adjunct Professor, Department of Neurology

    University of Washington

    Box 359608 | 325 Ninth Ave. | Seattle, WA 98104

    Clinic 206.744.2020 (#2,#0)

     




    Original Message


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